Incidence rate and spatio-temporal clustering of type 1 diabetes in Santiago, Chile, from 1997 to 1998

Revista de Saúde Pública

Jl Santos²  E Carrasco¹  Al Moore²  F Pérez-bravo²  C Albala² 

[1] ,Universidad de Chile Instituto de Nutrición y Tecnologia de Alimentos Santiago,Chile

关键词: Diabetes mellitus;    insulin-dependent;    Space-time clustering;    Incidence;    Child;    Adolescence;    Urban zones;    Diabetes mellitus insulino-dependente;    Conglomerados espaço-temporais;    Incidência;    Criança;    Adolescência;    Zonas urbanas;   

DOI  :  10.1590/S0034-89102001000100014

来源: SciELO

【 摘 要 】

OBJECTIVE: To estimate the incidence rate of type 1 diabetes in the urban area of Santiago, Chile, from March 21, 1997 to March 20, 1998, and to assess the spatio-temporal clustering of cases during that period. METHODS: All sixty-one incident cases were located temporally (day of diagnosis) and spatially (place of residence) in the area of study. Knox's method was used to assess spatio-temporal clustering of incident cases. RESULTS: The overall incidence rate of type 1 diabetes was 4.11 cases per 100,000 children aged less than 15 years per year (95% confidence interval: 3.06--5.14). The incidence rate seems to have increased since the last estimate of the incidence calculated for the years 1986--1992 in the metropolitan region of Santiago. Different combinations of space-time intervals have been evaluated to assess spatio-temporal clustering. The smallest p-value was found for the combination of critical distances of 750 meters and 60 days (uncorrected p-value = 0.048). CONCLUSIONS: Although these are preliminary results regarding space-time clustering in Santiago, exploratory analysis of the data method would suggest a possible aggregation of incident cases in space-time coordinates.

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