3D DCE-MRA of pedal arteries in patients with diabetes mellitus

2nd International Conference and Young Scientist School "Magnetic resonance imaging in biomedical research"

Zamyshevskaya, M.^1 ; Zavadovskaya, V.^1 ; Zorkaltsev, M.^1 ; Udodov, V.^1 ; Grigorev, E.^1

Department of Radiology and Radiotherapy, Siberian State Medical University, Tomsk, Russia^1

关键词: Diabetes mellitus;    Diabetic patient;    Enhanced contrast;    Identification and evaluation;    Imaging analysis;    MR angiography;    Treatment planning;    Vascularization;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/677/1/012010/pdf
DOI  :  10.1088/1742-6596/677/1/012010

来源: IOP

【 摘 要 】

Purpose was identification and evaluation of pedal vascularization in diabetic patients of using contrast MR-angiography (3D DCE-MRA). 23 diabetic feet of 23 patients (15 male, 8 female; mean age 56 ± 14.6) underwent 3D DCE-MRA (Gadobutrol 15ml) at 1.5 T. Imaging analysis included blood-flow's speed, vascular architectonic's condition and character of contrast's accumulation. Osteomyelitis was verified by surgery in 15 cases. All patients were divided in 3 groups: neuropathic, neuroischemic, ischemic forms of diabetic foot. First- pass MRA detected significant delay of contrast's arrival in ischemic group. There were no significant differences between the values of neuropathic and neuroischemic forms of diabetic foot. Pedal vessels in patients were absent. Contrast MRA revealed three types of contrast distribution in soft tissues: uniform, local increase and local absence. Osteomyelitis was associated with diffuse enhanced contrast accumulation in all cases. In summary, MRI blood vessel imaging is a promising and valuable method for examining peripheral arterial changes in diabetic foot and might be useful for treatment planning in different forms of diabetic foot.