Marine Drugs | |
A Possible Mechanism of Action of the Chemopreventive Effects of Sarcotriol on Skin Tumor Development in CD-1 Mice | |
Vipra Kundoor1  Xiaoying Zhang1  Sherief Khalifa2  Hesham Fahmy1  | |
[1] Department of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA. Tel.: 605-688-4247, Fax 605-688-5993;Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt | |
关键词: Cancer chemoprevention; Skin cancer; Sarcoptriol; Apoptosis; COX-2; | |
DOI : 10.3390/md404274 | |
来源: mdpi | |
【 摘 要 】
Sarcophine derivatives have been suggested to be chemopreventive in nature. One of its derivatives, Sarcotriol (ST), was investigated to study the skin cancer chemopreventive effects in female CD-1 mice. Three groups (control, promotion, initiation) of 30 female CD-1 mice each were taken. Carcinogenesis was initiated with 7, 12- dimethylbenz (a) anthracene (DMBA) and promoted with 12-
【 授权许可】
Unknown
© 2006 by MDPI
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