Chiral Symmetry Breaking Phenomenon Caused by a Phase Transition

Symmetry

Rui Tamura¹  Sekai Iwama¹ 

[1] Graduate School of Human and Environmental Studies, Kyoto University, Kyoto 606-8501, Japan

关键词: preferential enrichment;    enantiomeric resolution;    optical resolution;    chiral separation;    polymorphic transition;    epitaxial transition;    mixed crystal;   

DOI  :  10.3390/sym2010112

来源: mdpi

【 摘 要 】

We report the mechanism and scope of “preferential enrichment”, which is an unusual symmetry-breaking enantiomeric resolution phenomenon that is initiated by the solvent-assisted solid-to-solid transformation of a metastable polymorphic form into a thermodynamically stable one during crystallization from the supersaturated solution of certain kinds of racemic mixed crystals (i.e., solid solutions or pseudoracemates) composed of two enantiomers. The mechanism can well be interpreted in terms of a symmetrybreaking complexity phenomenon involving multistage processes that affect each other.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.