Roles of EphA2 in Development and Disease

Genes

Jeong Eun Park¹  Alexander I. Son¹ 

[1] Susan Lehman-Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA;

关键词: EphA2;    ephrin;    development;    cataract;    kidney;    bone;    ear;    mammary gland;   

DOI  :  10.3390/genes4030334

来源: mdpi

【 摘 要 】

The Eph family of receptor tyrosine kinases (RTKs) has been implicated in the regulation of many aspects of mammalian development. Recent analyses have revealed that the EphA2 receptor is a key modulator for a wide variety of cellular functions. This review focuses on the roles of EphA2 in both development and disease.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.