Antimicrobial and Antioxidant Activities and Phenolic Profile of Eucalyptus globulus Labill. and Corymbia ficifolia (F. Muell.) K.D. Hill & L.A.S. Johnson Leaves

Molecules

Ștefan Dezsi⁵  Alexandru Sabin Bွărău⁴  Cristina Bischin¹  Dan Cristian Vodnar²  Radu Silaghi-Dumitrescu¹  Ana-Maria Gheldiu³  Andrei Mocan³  Laurian Vlase³ 

[1] Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, 11, A. Janos Street, Cluj-Napoca 400028, Romania; E-Mails:;Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 3-5, Manăştur Street, Cluj-Napoca 400372, Romania; E-Mail:;Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 8, V. Babes Street, Cluj-Napoca 400010, Romania; E-Mail:;Faculty of Environmental Sciences and Engineering, Babeș-Bolyai University, 30, Fântânele Street, Cluj-Napoca 400294, Romania; E-Mail:;Faculty of Geography, Babeș-Bolyai University, 5-7, Clinicilor Street, Cluj-Napoca 400006, Romania; E-Mail:

关键词: Eucalyptus globulus;    Corymbia ficifolia;    antimicrobial;    antioxidants;    phenolics;   

DOI  :  10.3390/molecules20034720

来源: mdpi

【 摘 要 】

This study was performed to evaluate the in vitro antimicrobial and antioxidant activities and the phenolic profile of Eucalytus globulus Labill. and Corymbia ficifolia (F. Muell.) K.D. Hill & L.A.S. Johnson leaves. Both leave extracts contain significant amounts of phenolic compounds, mainly flavonoids. Qualitative and quantitative analyses of the phenolic compounds were performed using a HPLC/MS method. The main flavonoid was hyperoside and its highest amount was found in E. globulus (666.42 ± 5.02 μg/g dw plant material). Regarding the flavonol profile, myricetin was the dominant compound and its highest amount was found in C. ficifolia leaves (124.46 ± 0.24 μg/g dw plant material). The antioxidant activity was evaluated by DPPH, TEAC, hemoglobin ascorbate peroxidase activity inhibition (HAPX) and inhibition of lipid peroxidation catalyzed by cytochrome c assays, revealing an important antioxidant potential for both species. In the antimicrobial assays, C. ficifolia extract was found to be more active than E. globulus against both Gram-positive and Gram-negative bacterial strains with the exception of Bacillus subtilis. The results of the present study provide new valuable data regarding the bioactivities of these medicinal species.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.