Ventilatory Function in Young Adults and Dietary Antioxidant Intake

Nutrients

Vanessa Garcia-Larsen¹  Hugo Amigo³  Patricia Bustos³  Ioannis Bakolis² 

[1]Respiratory Epidemiology, Occupational Medicine, and Public Health Group, National Heart & Lung Institute, Imperial College London, London, SW3 6LR, UK

[2]MRC-HPA Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1NY, UK

[3] E-Mail:

[4]Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, Santiago, Chile

[5] E-Mails:

关键词: antioxidants;    flavonoids;    FFQ;    lung function;    young adults;    general population;   

DOI  :  10.3390/nu7042879

来源: mdpi

【 摘 要 】

Dietary antioxidants may protect against poor ventilatory function. We assessed the relation between ventilatory function and antioxidant components of diet in young Chileans. Forced expiratory volume in 1 s (FEV₁), forced vital capacity (FVC), and the ratio FEV₁/FVC were measured in 1232 adults aged 22–28 years, using a Vitalograph device. Dietary intake was ascertained with a food frequency questionnaire (FFQ) designed for this study, from which nutrient and flavonoid intakes were estimated. Dietary patterns were derived with Principal Component Analysis (PCA). After controlling for potential confounders, dietary intake of total catechins was positively associated with FVC (Regression coefficient (RC) of highest vs. lowest quintile of intake 0.07; 95% CI 0.01 to 0.15; p per trend 0.006). Total fruit intake was related to FVC (RC of highest vs. lowest quintile 0.08; 95% CI 0.003 to 0.15; p per trend 0.02). Intake of omega 3 fatty acids was associated with a higher FEV₁ (RC for highest vs. lowest quintile 0.08; 95% CI 0.01 to 0.15 L; p per trend 0.02) and with FVC 0.08 (RC in highest vs. lowest quintile of intake 0.08, 95% CI 0.001 to 0.16; p per trend 0.04). Our results show that fresh fruits, flavonoids, and omega 3 fatty acids may contribute to maintain ventilatory function.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.