International Journal of Molecular Sciences | |
Synthesis and Biological Evaluation of Novel Dehydroabietic Acid Derivatives Conjugated with Acyl-Thiourea Peptide Moiety as Antitumor Agents | |
Le Jin1  Hong-En Qu1  Xiao-Chao Huang1  Ying-Ming Pan1  Dong Liang1  Zhen-Feng Chen1  Heng-Shan Wang1  Ye Zhang1  | |
[1] State Key Laboratory Cultivation Base for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry & Pharmaceutical Science of Guangxi Normal University, Yucai Road 15, Guilin 541004, China; E-Mails: | |
关键词: dehydroabietic acid; chiral amino acid; thioureas; antitumor activity; apoptosis; | |
DOI : 10.3390/ijms160714571 | |
来源: mdpi | |
【 摘 要 】
A series of dehydroabietic acid (DHAA) acyl-thiourea derivatives were designed and synthesized as potent antitumor agents. The
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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