New Scalarane Sesterterpenoids from the Formosan Sponge Ircinia felix

Marine Drugs

Ya-Yuan Lai³  Mei-Chin Lu³  Li-Hsueh Wang³  Jih-Jung Chen¹  Lee-Shing Fang⁴  Yang-Chang Wu²  Ping-Jyun Sung³ 

[1] Department of Pharmacy & Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 907, Taiwan; E-Mail:;School of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, Taiwan;Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan; E-Mails:;Department of Sport, Health and Leisure, Cheng Shiu University, Kaohsiung 833, Taiwan; E-Mail:

关键词: Ircinia felix;    sponge;    scalarane;    sesterterpenoid;    cytotoxicity;   

DOI  :  10.3390/md13074296

来源: mdpi

【 摘 要 】

Five new scalarane sesterterpenoids, felixins A–E (1–5), were isolated from the Formosan sponge Ircinia felix. The structures of scalaranes 1–5 were elucidated on the basis of spectroscopic analysis. Cytotoxicity of scalaranes 1–5 against the proliferation of a limited panel of tumor cell lines was evaluated.

【 授权许可】

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.