Addition of CFCl3 to Aromatic Aldehydes via in Situ Grignard Reaction

Molecules

Balaka Barkakaty²  Bandana Talukdar¹  Bradley S. Lokitz² 

[1] Independent Researcher, Juripar, Panjabari, Guwahati 781037, Assam, India; E-Mail:;Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, One Bethel Valley Road, Oak Ridge, TN 37831, USA; E-Mail:

关键词: CFCl₃;    magnesium;    Grignard reaction;    in-situ process;    aromatic aldehydes;   

DOI  :  10.3390/molecules200815098

来源: mdpi

【 摘 要 】

Synthetic modification of trichlorofluoromethane (CFCl₃) to non-volatile and useful fluorinated precursors is a cost-effective and an environmentally benign strategy for the safe consumption/destruction of the ozone depleting potential of the reagent. In this report, we present a novel method for in situ Grignard reaction using magnesium powder and CFCl₃ for synthesis of dichlorofluoromethyl aromatic alcohols.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.