DIFLUORPHOS and SYNPHOS in asymmetric catalysis: Synthetic applications

Journal of Chemical Sciences

Phannarath Phansavath¹  Sebastien Prevost¹  Tahar Ayad¹  Virginie Ratovelomanana-Vidal1¹  Jean-Pierre Genet¹ 

[1] Institut de Recherche de Chimie Paris, CNRS - Chimie ParisTech, 11 rue Pierre et Marie Curie, 75231 Paris Cedex 05, France$$

关键词: Hydrogenation;    asymmetric catalysis;    total synthesis;    atropisomeric phosphines.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Enantiomerically pure diphosphines play an important role in various homogeneous metalcatalyzed asymmetric reactions. Over the last few years, our group has been involved in the design and synthesis of atropisomeric ligands named SYNPHOS and DIFLUORPHOS with complementary stereoelectronic properties. This paper shows the high catalytic performances of DIFLUORPHOS, SYNPHOS and SYNPHOS analogues for some C-H and C-C bond forming processes as well as for the synthesis of biorelevant targets.

【 授权许可】

Unknown