Synthesis of C-Arylnucleoside Analogues

Molecules

Christophe Len¹  Gérald Enderlin¹ 

[1] Sorbonne Universités, Université de Technologie de Compiègne, Ecole Supérieure de Chimie Organique et Minérale, Transformations Intégrées de la Matière Renouvelable, Centre de Recherche Royallieu, CS 60319, Compiègne cedex F-60203, France; E-Mail:

关键词: C-arylnucleoside;    nucleoside;    carbohydrate;    total synthesis;    asymmetric catalysis;   

DOI  :  10.3390/molecules20034967

来源: mdpi

【 摘 要 】

Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.