The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae

FEBS Letters

Lecrenier, Nicolas¹  Purnelle, Bénédicte¹  Foury, Françoise¹  Roganti, Tiziana¹ 

[1] Unité de Biochimie Physiologique, Place Croix du Sud 2–20, 1348 Louvain-la-Neuve, Belgium

关键词: Saccharomyces cerevisiae;    Mitochondrial DNA;    Sequence;    Polymorphism;    ORF;    open reading frame;   

DOI  :  10.1016/S0014-5793(98)01467-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The currently available yeast mitochondrial DNA (mtDNA) sequence is incomplete, contains many errors and is derived from several polymorphic strains. Here, we report that the mtDNA sequence of the strain used for nuclear genome sequencing assembles into a circular map of 85 779 bp which includes 10 kb of new sequence. We give a list of seven small hypothetical open reading frames (ORFs). Hot spots of point mutations are found in exons near the insertion sites of optional mobile group I intron-related sequences. Our data suggest that shuffling of mobile elements plays an important role in the remodelling of the yeast mitochondrial genome.

【 授权许可】

Unknown