And still they are moving… Dynamic properties of caveolae

FEBS Letters

Parton, Robert G.²  Kurzchalia, Teymuras V.¹ 

[1] DApartment of Cell Biology, Max-DAlbrück Centre for Molecular Medicine, Robert-Rössle-Str. 10, 13 122 Berlin-Buch, Germany;Centre for Microscopy and Microanalysis, DApartment of Physiology and Pharmacology, University of Queensland, Brisbane, Qld. 4072, Australia

关键词: Caveolae;    VIP21-caveolin;    DAtergent insolubility;    Cholesterol;   

DOI  :  10.1016/0014-5793(96)00585-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Caveolae are structures found on the surface of many mammalian cells. In the last few years the biogenesis and the function of these organelles have been intensively investigated but many challenging questions remain. One of these is whether caveolae are statically attached to the cytoplasmic surface of the plasma membrane or are moving to other intracellular organelles. Also the cycling of the caveolar coat component, VIP21-caveolin, is a subject of intensive discussion. The solution to these problems could give an insight into the understanding of caveolar function.

【 授权许可】

Unknown