Insect calcium channels

FEBS Letters

Glossmann, Hartmut¹  Schulz, Cordula²  Rosentha, Friederike¹  Bachmann, Andreas¹  Striessnig, Jörg¹  Grabner, Manfred¹  Tautz, Diethard² 

[1] Institut für Biochemische Pharmakologie, Universität znnsbruck, Peter Mayrstraβe 1, A-6020 Innsbruck, Austria;Institut für Zoologie, Universität München, Luisenstraβe 14, 8000 München 2, Germany

关键词: Calcium channel;    cDNA cloning;    Hybridization (in situ);    Body wall muscle;    Phylogenetic tree;    DHP;    dihydropyridine;    DIG;    digoxigenin-11-dUTP;    Mdlα1;    Musca domestica larvae α1-subunit;    PAA;    phenylalkylamines;    PCR;    polymerase chain reaction;    SDS;    sodium dodecyl sulfate;   

DOI  :  10.1016/0014-5793(94)80413-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The complete amino acid sequence of an invertebrate calcium channel α-subunit from housefly (Musca domestica) larvae (designated Mdlα₁) has been deduced by cDNA cloning and sequence analysis. Mdlα₁ shares higher percent sequence identity with 1,4-dihydropyridine (DHP)-sensitive L-type than with DHP-insensitive calcium channels. As shown by whole mount in situ hybridization and immunostaining Mdlα, is predominantly expressed in the larval body wall musculature.

【 授权许可】

Unknown