p33, an endogenous target protein for arginine‐specific ADP‐ribosyltransferase in chicken polymorphonuclear leukocytes, is highly homologous to mim‐1 protein (myb‐induced myeloid protein‐1)

FEBS Letters

Shimoyama, Makoto¹  Yamada, Kazuo¹  Mishima, Koichi²  Tsuchiya, Mikako¹ 

[1] Department of Biochemistry, Shimane Medical University, Izuno 693, Japan;Department of Oral and Maxillofacial Surgery, Shimane Medical University, Izuno 693, Japan

关键词: Polymorphonuclear leukocyte (chicken);    Myb;    Cell differentiation;    ADP-ribosylation;    EDTA;    ethylene diamine tetraacetic acid;    TFA;    trifluoroacetic acid;    PCR;    polymerase chain reaction;    HPLC;    high performance liquid chromatography;   

DOI  :  10.1016/0014-5793(92)81102-R

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have determined the partial amino acid sequence of p33, an endogenous substrate protein for arginine-specific ADP-ribosyltransferase in chicken polymorphonuclear leukocytes (heterophils), and found that the sequence was completely identical with the regions of amino acid sequences deduced from mim-1 (named for myb-induced myeloid protein-1, which is expressed in chicken promyelocytes) cDNA [(1989) Cell, 59, 1115–1125], except for one amino acid difference (Tyr²⁹⁷→Ile). These results together with data on cellular and subcellular distributions of p33 in heterophils suggest that mim-1 may encode the precursor protein of p33.

【 授权许可】

Unknown