Scapharca hemoglobins, type cases of a novel mode of chain assembly and heme‐heme communication

FEBS Letters

Barra, Donatella²  Bossa, Francesco²  Petruzzelli, Raffaele¹  Chiancone, Emilia²  Boffi, Alberto²  Ascoli, Franca³ 

[1] Department of Biology, Department of Biochemical Sciences, University La Sapienza, 00185 Rome, Italy;CNR Center of Molecular Biology, Department of Biochemical Sciences, University La Sapienza, 00185 Rome, Italy;Department of Experimental Medicine and Biochemical Sciences, University Tor Vergata, 00173 Rome, Italy

关键词: Molluscan hemoglobin;    Amino acid sequence;    Hemoglobin assembly;   

DOI  :  10.1016/0014-5793(89)81512-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The sequences of the A and B chains of the Scapharca inaequivalvis tetrameric hemoglobin (HbII) are reported. They are homologous to the corresponding chains of other Arcid hemoglobins. Moreover, a comparison of the present data with the sequence of the S. inaequivalvis dimeric hemoglobin (HbI), for which high-resolution X-ray data are available, allows the identification of the residues that direct the assembly of the two components and of those that may be involved in the interdimeric contacts.

【 授权许可】

Unknown