Voltage‐dependent transient calcium currents in freshly dissociated capillary endothelial cells

FEBS Letters

Tanzi, F.¹  Rodeau, J.-L.¹  Bossu, J.-L.¹  Feltz, A.¹ 

[1] Laboratoire d'Etude des Régulations Physiologiques, Centre National de la Recherche Scientifique, 23 rue Becquerel, F-67087 Strasbourg, France

关键词: Bovine endothelial cell;    Calcium current;    Patch-clamp;    Fura-2;   

DOI  :  10.1016/0014-5793(89)81126-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Dissociated capillary endothelial cells display a voltage-dependent Ca current activating around the resting potential. The initial transient component of the current corresponds to a Ca channel of the T type. Some cells also display a plateau component corresponding to a distinct dihydropyridine-sensitive Ca channel. Depolarization induced by high external K⁺ elicits an increase in cytoplasmic Ca concentration. Confluent cells have been found to express the same Ca permeabilities.

【 授权许可】

Unknown