Tuftsin stimulates growth of HL60 cells

FEBS Letters

Najjar, Victor A.¹  Bump, Nancy J.¹ 

[1] Division of Protein Chemistry, Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA

关键词: Tuftsin;    Growth;    (HL60 cell);    ATCC;    American Type Culture Collection;    FCS;    fetal calf serum;    PBS;    phosphate buffered;    saline;    PMN;    polymorphonuclear leukocyte;    TFMS;    trifluoromethanesulfonic acid;   

DOI  :  10.1016/0014-5793(88)81444-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Many functions of monocyte/macrophage and granulocyte are activated by tuftsin; principally phagocytosis, motility, immunogenic stimulation, antibacterial and antineoplastic activities. Here it is shown that tuftsin stimulates HL60 growth to twice the control rate. The uptake of [³H]uridine and [³H]leucine in a pulse of 30 min was also double that of the control. The uptake of thymidine was not stimulated.

【 授权许可】

Unknown