A new 5′‐non‐coding region for human placental insulin‐like growth factor II mRNA expression

FEBS Letters

Dreyer, D.²  Le Bouc, Y.¹  Sondermeijer, P.²  Binoux, M.¹  Noguiez, P.¹  Girard, F.¹ 

[1] INSERM U 142, Hôpital Trousseau, 26 av. Dr Netter, 75012 Paris France;Transgène SA, 11 rue de Molsheim 67000 Strasbourg, France

关键词: Insulin-like growth factor II;    Somatomedin;    cDNA cloning;    Intron splicing;    (Human placenta);   

DOI  :  10.1016/0014-5793(87)80216-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A human placenta cDNA library was screened for insulin-like growth factor II (IGF-II). Four clones were selected, which exhibited an IGF-II cDNA coding sequence identical to those previously described for human adult liver IGF-II cDNA. Extensive sequence diversity was observed in the 5′-non-coding region, probably resulting from differential intron splicing.

【 授权许可】

Unknown