Discovery of a γ‐carboxyglutamic acid‐containing protein in human spermatozoa

FEBS Letters

Vermeer, Cees¹  de Boer-van den Berg, Marian A.G.¹  Soute, Berry A.M.¹  Ulrich, Magda¹  Müller-Esterl, Werner¹ 

[1] Department of Biochemistry, University of Limburg, PO Box 616, 6200 MD Maastricht, The Netherlands

关键词: Vitamin K;    Carboxylase;    Warfarin;    Sperm;    γ-Carboxyglutamic acid;   

DOI  :  10.1016/0014-5793(85)80444-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Here we describe the identification of a γ-carboxyglutamic acid-containing protein in human spermatozoa. After thermal decarboxylation the protein is a good substrate for vitamin K-dependent carboxylase from various origins. A quick purification procedure for the decarboxylated protein is presented and in a preliminary characterization we have established its M _r, (28000–30000) and its amino acid composition.

【 授权许可】

Unknown