Identity of the metal ligands in the manganese‐ and iron‐containing superoxide dismutases

FEBS Letters

Barra, D.²  Bannister, J.V.¹  Schinina, M.E.²  Bossa, F.² 

[1] Inorganic Chemistry Laboratory, University of Oxford, Oxford OX1 3QR, England;Institute of Biological Chemistry and CNR Centre for Molecular Biology, University of Rome, 00185 Rome, Italy

关键词: Superoxide dismutase;    Manganese;    Iron;    Amino acid sequence;    Metal ligand;   

DOI  :  10.1016/0014-5793(85)80545-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Alignment of the amino acid sequence of peptides obtained following digestion of Photobacterium leiognathi iron Superoxide dismutase with the known sequence of Bacillus stearothermophilus manganese superoxide dismutase shows that the residues found to form ligands to the manganese are conserved in the iron enzyme. This indicates that the metal ligands in both proteins are identical.

【 授权许可】

Unknown