The inhibitor ribonucleoprotein of poly(A)‐containing non‐polysomal messenger ribonucleoprotein of A. salina cryptobiotic embryos

FEBS Letters

Piot, Etienne¹  Backhovens, Hubert¹  Slegers, Herman¹ 

[1] Department of Biochemistry, University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk, Belgium

关键词: iRNP;    mRNP;    Protein synthesis;    Hepes;    4-(2-hydroxyethyl)-l-piperazine-ethane sulfonic acid;    iRNA;    inhibitor ribonucleic acid;    iRNP;    inhibitor ribonucleoprotein;    mRNP;    messenger ribonucleoprotein;    PMSF;    phenylmethylsulfonyl fluoride;    DTT;    dithiothreitol;   

DOI  :  10.1016/0014-5793(84)80560-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The inhibitor is a ribonucleoprotein sedimenting at 5–6 S with a M _r, of ~ 84 000 ± 6000. The particle is composed of a protein with M _r of 64 000 and an RNA with a length of 85 ± 2 nucleotides and is a very potent inhibitor of the translation of mRNA. The inhibition is a property of the RNA but the inhibitor ribonucleoprotein is more efficient in the inhibition of poly(A) containing mRNA than its extracted RNA.

【 授权许可】

Unknown