Noradrenaline controls the concentration of the uncoupling protein in brown adipose tissue

FEBS Letters

Mory, G.¹  Bouillaud, F.¹  Combes-George, M.¹  Ricquier, D.¹ 

[1] Laboratoire de Physiologie Comparée (CNRS-LA 307), Université Pierre et Marie Curie, 4 Place Jussieu, F-75230 Paris Cédex 05, France

关键词: Noradrenaline;    Brown adipose tissue;    Mitochondria;    Uncoupling protein;    Neurotrophism;   

DOI  :  10.1016/0014-5793(84)80120-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The importance of noradrenaline in the control of the level of the uncoupling protein responsible for the high thermogenic capacity of brown adipose tissue mitochondria was examined. It was observed that chronic infusion of noradrenaline through mini-osmotic pumps increased the mitochondrial concentration of this uncoupling protein to the same extent as chronic exposure to cold.

【 授权许可】

Unknown