期刊论文详细信息
Journal of the Korean Chemical Society
Synthesis and Biological Evaluation of Novel Isopropyl 2-thiazolopyrimidine-6-carboxylate Derivatives
C V Rao1  K Naga Raju1  S B Jonnalagadda1  Suresh Maddila1  Y Kotaiah1  N Hari Krishna1 
关键词: Isopropyl 2-thiazolopyrimidine-6-carboxylate;    Anti-inflammatory;    Antibacterial;    Antifungal activities;   
DOI  :  
学科分类:化学(综合)
来源: Korean Chemical Society
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【 摘 要 】

In the present study, we have synthesized novel Isopropyl 2-(4-substitutedbenzylidene)-5-methyl-3-oxo-7-phenyl- 3,7-dihydro-2H-thiazolo[3,2-a]-pyrimidine-6-carboxylate derivatives (6a-j). Elemental analysis, IR, 1H NMR and mass spectral data elucidated structure of newly synthesized compounds. The newly synthesized compounds were screened for antiinflammatory and anti microbial studies. Their biological activity data of the 10 compounds indicates that two compounds posses potent anti-inflammatory and five have antimicrobial activities.

【 授权许可】

Unknown   

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