A Yersinia Effector with Enhanced Inhibitory Activity on the NF-κB Pathway Activates the NLRP3/ASC/Caspase-1 Inflammasome in Macrophages

PLOS Pathogens

Ruslan Medzhitov¹  Ying Zheng¹  James B. Bliska¹  Sarit Lilo¹  Yue Zhang¹  Kenneth B. Marcu¹  Igor E. Brodsky¹ 

关键词: Macrophages;    Apoptosis;    Yersinia pestis;    Secretion;    Enzyme-linked immunoassays;    Yersinia pseudotuberculosis;    Inflammasomes;    MAPK signaling cascades;   

DOI  :  10.1371/journal.ppat.1002026

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

Unknown