Stable Cytotoxic T Cell Escape Mutation in Hepatitis C Virus Is Linked to Maintenance of Viral Fitness

PLOS Pathogens

Luke Uebelhoer¹  Naglaa H. Shoukry¹  Charles M. Rice¹  Jin-Hwan Han¹  Arash Grakoui¹  Holly L. Hanson¹  Christopher M. Walker¹  Guaniri Mateu¹  Benoit Callendret¹ 

关键词: T cells;    Cytotoxic T cells;    Viral replication;    Microbial mutation;    Cloning;    Hepatitis C virus;    Chimpanzees;    Substitution mutation;   

DOI  :  10.1371/journal.ppat.1000143

学科分类：生物科学（综合）

来源: Public Library of Science

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