Viral CTL Escape Mutants Are Generated in Lymph Nodes and Subsequently Become Fixed in Plasma and Rectal Mucosa during Acute SIV Infection of Macaques

PLOS Pathogens

Jessica C. Engram¹  Nichole R. Klatt¹  David A. Garber¹  Michael R. Betts¹  Mark B. Feinberg¹  Richard M. Dunham¹  Guido Silvestri¹  Thomas H. Vanderford¹  Chelsea Bleckwehl¹ 

关键词: Cytotoxic T cells;    T cells;    Viral replication;    SIV;    Immune response;    Blood plasma;    Microbial mutation;    Lymph nodes;   

DOI  :  10.1371/journal.ppat.1002048

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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