A Study on Borna Disease Virus Infection in Domestic Cats in Japan

Journal of Veterinary Medical Science

Takashi KIMURA³  Atsushi MATSUDA⁴  Yasuyuki TANAHASHI³  Yoshii NISHINO³  Ryoko FUKUSHIMA⁷  Michiko YOSHIDA⁷  Azusa SOMEYA³  Misuzu SEO³  Hiroshi HIRAMI⁵  Goro KURITA²  Reiko IIZUKA⁵  Masayuki FUNABA¹  Tangmunkhong PRAPEUK⁷  Shunichi TAKAHASHI⁶ 

[1]Division of Applied Biosciences, Kyoto University Graduate School of Agriculture, Kitashirakawa Oiwakecho, Kyoto 606�?8502, Japan

[2]Kurita Animal Hospital, 139�?1 Furukawa, Furukawa 306�?0016, Japan

[3]Department of Animal Medical Sciences, Faculty of Life Sciences, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603�?8555, Japan

[4]Hoshigaoka Animal Hospital, 4�?4�?5 Hoshigaoka, Chuo-ku, Sagamihara 252�?0238, Japan

[5]Hirami Animal Hospital, Tateno-cho, Nerima-Ku, Tokyo 177�?0054, Japan

[6]FAH Takahashi Animal Hospital, 1785�?1 Shimotsuruma, Yamato 242�?0001, Japan

[7]Research Institute of Biosciences, Azabu University, 1�?17�?71 Fuchinobe, Chuo-ku, Sagamihara 252�?5201, Japan

关键词: antibody;    Borna disease virus;    epidemiology;    feline;    vertical transmission;   

DOI  :  10.1292/jvms.13-0349

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(16)Borna disease virus (BDV) infection causes neurological disease in cats. Here, we report BDV infection in 199 hospitalized domestic cats in the Tokyo area. BDV infection was evaluated by detection of plasma antibodies against BDV-p24 or -p40. BDV-specific antibodies were detected in 54 cats (27.1%). Interestingly, the percentage of seropositive cats was not significantly different among the three clinical groups, i.e., healthy (29.8%), neurologically asymptomatic disease (22.2%) and neurological disease (33.3%). The specific antibodies were present even in cats aged below one year. The seropositive ratio was constant, irrespective of age and sampling season. The present study suggests that additional factors are required for onset of Borna disease in naturally infected cats and that BDV is transmitted through vertical routes in cats.

【 授权许可】

Unknown