Association between calcium intake, parathormone levels and blood pressure during pregnancy.

Colombia Médica

Julián A. Herrera⁴  Ignacio Arribas⁵  Julia Alvarez³  Roberto Matorras²  Aníbal Nieto³  José Villar⁶  Carlos López de la Manzanara⁵  Eugenia Peiró¹ 

[1] Universidad de Alcalá;Universidad del País Vasco;Universidad de Alcalá;Universidad del Valle;Universidad de Alcalá,;WHO

关键词: Calcium intake;    Endothelin;    PTH: PTH-rp;    Preeclampsia;    Nitric oxide;   

DOI  :  

学科分类：医学（综合）

来源: Universidad del Valle * Facultad de Salud / Universidad del Valle, Faculty of Health

【 摘 要 】

Purpose :To evaluate the association between calcium intake from diet, calciotropic hormones (PTH, PTH-rp), vasoactive regulators (endothelin, nitric oxide) and blood pressure levels during pregnancy, birth and puerperium. Method: In a prospective study 149 healthy normotensive primigravidas were followed-up from 15 weeks of gestation to puerperium. Daily calcium intake, calciuria, PTH, PTH-rp, endothelin, nitrite-nitrate, and Holter Test were assessed. Linear regression models were performed to evaluate the association between calcium intake, blood pressure levels and the laboratory tests. Multivariate regression models were performed to control potential confounders. Results: A significant increase of calcium intake during pregnancy was observed (931±301 mg/day to 1,195±467 mg/day, pConclusion: Low calcium intake during pregnancy is associated with a larger increase of systolic blood pressure and high parathormone levels.

【 授权许可】

Unknown