Low calcium intake is associated with increased bone resorption in postmenopausal Japanese women: Yokogoshi Study

Public Health Nutrition

Yasuo Tsuchiya¹  Toshiko Saito¹  Kazutoshi Nakamura¹  Naoko Tsugawa¹  Toshio Okano¹  Miki Ishikawa¹  Keiko Maruyama¹  Ryosaku Kobayashi¹  Akihiro Yoshihara¹  Mari Oyama¹  Mitsue Nashimoto¹  Rieko Oshiki¹  Keiko Hyodo¹  Masaharu Yamamoto¹ 

关键词: Bone metabolism;    Bone resorption;    Calcium intake;    Postmenopause;   

DOI  :  10.1017/S1368980009005084

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

ObjectiveLow Ca intake is common among Japanese women, but its effect on bone metabolism has not been fully elucidated. The aim of the present study was to determine the relationship between Ca intake and serum markers of bone turnover in postmenopausal Japanese women.DesignA cross-sectional study.SettingA community setting.SubjectsSubjects were 595 home-dwelling postmenopausal Japanese women. Ca intake was assessed by a validated FFQ. Serum type I collagen cross-linked N-telopeptides (NTX) and osteocalcin were measured as markers of bone turnover. The relationships between demographic characteristics, lifestyles, serum Ca, vitamin D and intact serum parathyroid hormone and bone turnover were also assessed.ResultsThe average age of the subjects was 64·5 (sd 5·8) years and the mean Ca intake was 527 (sd 160) mg/d. Ca intake was significantly associated with serum NTX (P = 0·0104), but not with serum osteocalcin. Mean serum NTX concentration in the lowest quartile of Ca intake (

【 授权许可】

Unknown