Effect of Combination of Nano Herbal Andaliman (Zanthoxylum acanthopodium DC.) and Extra Virgin Olive Oil (EVOO) to Kidney Histology of Preeclampsia Rats

4th International Conference on Biological Sciences and Biotechnology

Situmorang, P.C.^1 ; Ilyas, S.^1 ; Hutahaean, S.^1

Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, Indonesia^1

关键词: Extra virgin olive oil;    PE modeling;    Preeclampsia;    Pregnant rat;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/305/1/012081/pdf
DOI  :  10.1088/1755-1315/305/1/012081

来源: IOP

【 摘 要 】

Preeclampsia is a pregnancy disorder that can cause interference in the kidneys. This study aims to determine the safety effects of the combination of Nano herbal Andaliman (Zanthoxylum acanthopodium) and Extra Virgin Olive Oil (EVOO) in preeclampsia. This study consisted of 5 groups ie K(-): Pregnant Rats, K(+):PE model Rats, P1: PE model Rats + 0,45g EVOO/day/200gBW at 13rd-19th days pregnancy, P2: PE mode Rats + Nano-Andaliman 100mg/200gBW at 13rd-19th days pregnancy and P3: PE model Rats + 0,45g EVOO/day/200gBW + Nano-Andaliman 100mg/200gBW at 13rd-19th days pregnancy. This study showed no differences in kidney weight (p>0,05) but there were significant differences in Necrosis in kidneys (p