Routes of entry of Piscirickettsia salmonis in rainbow trout Oncorhynchus mykiss

Diseases of Aquatic Organisms

P. A. Smith¹  J. Contreras¹  P. Pizarro¹  P. Ojeda¹  S. Oyanedel¹  J. Larenas¹ 

关键词: Piscirickettsia salmonis;    Pathogenesis;    Fish disease;    Salmonid;   

DOI  :  10.3354/dao037165

学科分类：生物科学（综合）

来源: Inter-Research

【 摘 要 】

ABSTRACT: Since 1989, Piscirickettsia salmonis, the causal agent of piscirickettsiosis, has killed millions of farmed salmonids each year in southern Chile. The portal of entry for the pathogen was investigated by use of selectedexperimental infections in juvenile rainbow trout (12 g). The methods used were intraperitoneal injection, subcutaneous injection, patch contact on skin, patch contact on gills, intestinal intubation and gastric intubation. Cumulative mortalities at Day33 post-inoculation were 98, 100, 52, 24, 24, and 2%, respectively. It was shown that intact skin and gills could be penetrated by P. salmonis. The high mortality obtained in subcutaneously injected fish indicated that skin injuries couldfacilitate the invasion of this pathogen. Results suggested that the main entry sites are through the skin and gills and that the oral route may not be the normal method by which P. salmonis initiates infection of salmonids.

【 授权许可】

Unknown