Node-positive Breast Cancer: Which Are the Best Chemotherapy Regimens?

Breast care

Harald Sommer¹  Klaus Friese¹  Brigitte Rack¹  Wolfgang Janni¹  Nadja Harbeck¹  Ingo Bauerfeind¹ 

[1] aFrauenkliniken Innenstadt und Großhadern, Klinikum der Ludwig-Maximilians-Universität, München

关键词: Chemotherapy;    Prognosis;    Recurrence;    Breast cancer;    Controversies;    Taxanes;    Anthracyclines;    Trastuzumab;   

DOI  :  10.1159/000149099

学科分类：泌尿医学

来源: S Karger AG

【 摘 要 】

Breast cancer-associated mortality has been significantly reduced since the 1990s, mainly because of early diagnosis and systemic therapeutic interventions. All three therapy components – cytostatic therapy, endocrine therapy and targeted antibody therapy – are at present necessary tools for the curative treatment of primary breast cancer. This article reviews the evidence base for the use of various chemotherapy schedules in patients with primary, node-positive breast cancer, including schedules in combination with targeted HER2/neu therapy.

【 授权许可】

Unknown