Detection and Characterization of Enteric Viruses in Flood Water from the 2011 Thai Flood

Japanese Journal of Infectious Diseases

Kazuyoshi Ikuta⁶  Ronald E. Morales Vargas³  Yuvadee Mahakunkijchareon⁴  Pornsawan Leaungwutiwong⁴  Pratap Singhasivanon⁵  Akifumi Yamashita²  Nathamon Ngaosuwankul⁴  Witawat Tunyong⁴  Tamaki Okabayashi¹  Narin Thippornchai⁴ 

[1] Mahidol-Osaka Center for Infectious Diseases, Faculty of Tropical Medicine, Mahidol University;Genome Information Research Center, Osaka University;Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University;Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University;Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University;Department of Virology, Research Institute for Microbial Diseases, Osaka University

关键词: enteric virus;    flood water;    Thailand;    waterborne viruses;    water contamination;   

DOI  :  10.7883/yoken.66.398

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(34)Cited-By(5)Severe flooding, which is associated with numerous outbreaks of a wide range of infectious diseases, particularly those caused by enteric viruses, occurred in all areas of Thailand in 2011. To determine the prevalence of five human enteric viruses, namely enterovirus, rotavirus (RV), norovirus (NV), hepatitis A virus (HAV), and hepatitis E virus, in the flood water, 100 water samples were collected from flood-damaged areas in central Thailand. Viral RNA was extracted from concentrated samples and analyzed by RT-PCR and sequencing. NV was the most commonly detected pathogen in the tested samples (14%). RV and HAV were detected in 9% and 7% of samples, respectively. This study is the first to detect enteric viral genes in flood water in Thailand. Furthermore, it is the first to detect an NV gene in any type of environmental water in Thailand. These results provide useful information for estimating the risk of flood waterborne viral infection.

【 授权许可】

Unknown