INCORPORATION OF OMEGA-3 FATTY ACID AND SYNTHESIS OF THEIR METABOLITES IN MUSCLE TISSUE IN MICE FED WITH FLAXSEED AND PERILLA-ENRICHED DIET | Science Publications

American Journal of Applied Sciences

Jesui Vergilio Visentainer¹  Marcia Machado de Oliveira Dalalio¹  Damila Rodrigues de Morais¹  Amarilis Giaretta de Moraes¹  Flavia Braidotti Stevanato¹  Jeane Eliete Laguila Visentainer¹  Sheisa Cyleia Sargi¹ 

关键词: Incorporation;    Omega-3;    Omega-6;    Supplementation;    Mice;   

DOI  :  10.3844/ajassp.2013.367.373

学科分类：自然科学（综合）

来源: Science Publications

【 摘 要 】

Polyunsaturated fatty acids omega 3 and omega 6 are believed to have beneficial physiological effects on the human body. The present study aimed to evaluate the incorporation and synthesis of omega-3 fatty acid and their metabolites in muscle tissue in mice fed with a flaxseed and perilla-enriched diet. The animals were fed a diet supplemented with flaxseed and perilla meals for fifty-six days and control animals received a commercial diet. Mice were sacrificed on the 7th, 28th and 56th days and the muscle tissue was collected. The FA concentration was analyzed by gas chromatography. The levels of alpha-Linolenic Acid (LNA) and their metabolites, Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) increased as a function of feeding length in the groups given the supplemented diet. LNA was incorporated into muscle tissue and conversion into Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFA) was observed. The muscle tissue of animals fed with enriched diets presented a high sum of n-3 FA and high concentrations of LNA, EPA and DHA, as compared to mice fed commercial diet. The intake of flaxseed and perilla-meal enriched diets by mice may result in the deposition of LNA and its metabolites EPA and DHA into muscle tissue.

【 授权许可】

Unknown