Magnetic Beads Actuating and Sensing by Light Addressability

Proceedings

Wu, Min-Hsien¹  Hong, Jia-Long²  Yang, Chia-Ming³  Chen, Yu-Ping⁴  Peng, Hsin-Yin⁵ 

[1] Biosensor Group, Biomedical Engineering Research Center, Chang Gung University, Taoyuan 333, Taiwan;Department of Mechanical Engineering, National Taiwan University, Taipei City 106, Taiwan;Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan City 333, Taiwan;Institute of Electro-Optical Engineering, Chang Gung University, Taoyuan 333, Taiwan;Office of Physical Education, Chang Gung University, Taoyuan 333, Taiwan

关键词: magnetic bead;    a-Si:H;    chemical image;    LAPS;   

DOI  :  10.3390/proceedings2131019

学科分类：社会科学、人文和艺术（综合）

来源: mdpi

【 摘 要 】

Micro particles and nanoparticles applied in microfluidics became a popular direction to improve biochip performance. Magnetic beads are the well-studied carriers including manipulation and surface modification, which could be easily to apply in biosensor development. A new methodology combined the actuators and sensor in the same chip all trigged by illumination is proposed in this study. A microfluidic chip with a-Si:H layer and ITO/glass with proper operation could be used to collect magnetic beads firstly and then following the optoelectrical measurement. In the meantime, 2D images for clusters of magnetic beads can be easily achieved with the addressable illumination. This proposed platform could own the high potential for a sensor array with better sensing performance.

【 授权许可】

CC BY