Antibiotic susceptibility and plasmid pattern of Pseudomonas aeruginosa from the surgical unit of a university teaching hospital in north central Nigeria

International Journal of Medicine and Medical Sciences

B. O. Olayinka¹  A. T. Olayinka²  B. A. Onile³ 

[1] Department of Medical Microbiology and Parasitology,University of Ilorin, Ilorin, Nigeria;Department of Medical Microbiology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.;Department of Pharmaceutics and Pharmaceutical Microbiology,Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria.

关键词: Antibiotic resistance;    plasmid;    Pseudomonas aeruginosa;   

学科分类：医学（综合）

来源: Academic Journals

【 摘 要 】

This study determined the susceptibility pattern and multiple antibiotic resistance (MAR) index of 92 Pseudomonas aeruginosa strains from clinical samples comprising mainly urine (51.1%) and wounds (41.3%) obtained from the surgical units of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria; over a 24-month period. The strains were susceptible to imipenem (94.6%), ciprofloxacin (90.2%), amikacin (89.1%) and ceftazidime (78.3%) but resistant to ofloxacin (82.6%), perfloxacin (58.7%) and gentamicin (35.8%). Analysis of the MAR index of isolates revealed that 60.9% had MAR index of 0.3 and above, which is an indication of probable origin from the hospital environment where antibiotics are extensively used. A strict management of antibiotic policies and a continuous surveillance programme for multidrug resistant pathogens like P. aeruginosa in specialised units is advocated.

【 授权许可】

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