Effects of D-allulose on glucose metabolism after the administration of sugaror food in healthy dogs

The Journal of Veterinary Medical Science

Masaaki TOKUDA¹  Toru NOMIZO²  Naohito NISHII²  Satoshi TAKASHIMA²  Hitoshi KITAGAWA²  Tatsuya MATSUBARA² 

[1] Department of Cell Physiology, Faculty of Medicine,Kagawa University, Kagawa, Japan;Joint Department of Veterinary Medicine, Faculty ofApplied Biological Sciences, Gifu University, 1–1 Yanagido, Gifu 501–1193,Japan

关键词: D-allulose;    dog;    glucose;    insulin;    rare sugar;   

DOI  :  10.1292/jvms.16-0302

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

D-allulose is a C-3 epimer of D-fructose and has recently been investigated for itshypoglycemic effects. In the present study, the effects of D-allulose on glucosemetabolism were evaluated in healthy dogs administrated sugar or food. The oraladministrations of D-allulose decreased plasma glucose concentrations after oral glucoseor maltose administration, with a diminished plasma insulin rise. The glucose suppressiveeffect of D-allulose was also observed after intravenous glucose administrations withoutincrease in plasma insulin concentration. In contrast, D-allulose showed no effect onplasma glucose and insulin concentrations after feeding. The present results suggest thatD-allulose administration may be beneficial in dogs with impaired glucose tolerance.Further studies investigating the therapeutic efficacy of D-allulose in diabetic dogs arerequired.

【 授权许可】

Unknown