An investigation of the potential for non-invasive optical measurements of glucose concentration in human subjects was conducted from March 1, 1997 to March 31, 1998. The investigation started with a study of current practice, market potential, activity in the field, and prior work, as evidenced by literature and patents. A feasibility study was conducted, a spectrograph was purchased, a sampling accessory was modified, measurements were made on a small sample of subjects, and the resulting data were analyzed. We reached conclusions on the business potential and the quality of our measurements, and we recommended a course of action for HP. 54 Pages