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Advances in Pulmonary Hypertension

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关键词: Recommended for You;    Journal Articles;    Pediatrics;    WHO Group 1- Pulmonary Arterial Hypertension;    PH Medications;    Gender;    PH;    early childhood;    bronchiolitis obliterans;    hematologic disorder;    Oral therapy;    Phosphodiesterase Inhibitors (PDE-5 Inhibitors);    Endothelin Receptor Antagonists;    nitric oxide;    endothelial dysfunction;    Testosterone;    Drug development;    clinical trial;    pre-clinical research;    Epidemiology;   

DOI  :  

学科分类：医学（综合）

来源: Pulmonary Hypertension Association

【 摘 要 】

Similarly, colorectal screening should probably only be considered in patients with very stable PAH, as current recommendations are for screening only in patients age 50 to 75 with a life expectancy greater than 10 years.3 Screening options include fecal occult blood testing, sigmoidoscopy, and colonoscopy, all of which have demonstrated a mortality benefit in other patient populations.3 The type of screening should also be carefully considered: colonoscopy is typically a preferred test in the general population, but it requires significant sedation which can pose a risk for PH patients. In addition to the other screening options above, CT-colonography is now also a recommended option that requires bowel preparation but no sedation.3 Therefore, while the lack of sedation makes this option attractive, the tolerability of the large amount of oral fluid needed for bowel preparation needs to be considered.

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