Antibacterial Composite Layers on Ti: Role of ZnO Nanoparticles

Archives of Metallurgy and Materials

A. Belcarz¹  M. Lewandowska²  P. Suchecki²  M. Andrzejczuk²  A. Roguska³ 

[1] Chair and Department of Biochemistry and Biotechnology, Medical University of Lublin, Lublin, Poland;Faculty of Material Science and Engineering, Warsaw University of Technology, Warszawa, Poland;Institute of Physical Chemistry, Polish Academy of Sciences, Warszawa , Poland

关键词: Keywords: bone implants;    TiO2 nanotubes;    ZnO nanoparticles;    Staphylococcus epidermidis;    antibacterial properties;   

DOI  :  10.1515/amm-2016-0039

学科分类：金属与冶金

来源: Akademia Gorniczo-Hutnicza im. Stanislawa Staszica / University of Mining and Metallurgy

【 摘 要 】

Problem of Post-operative infections of implant materials caused by bacterial adhesion to their surfaces is very serious. Enhancement of antibacterial properties is potentially beneficial for biomaterials value. Therefore, the metallic and metallic oxide nanoparticles attract particular attention as antimicrobial factors. The aim of this work was to create nanotubular (NT) oxide layers on Ti with the addition of ZnO nanoparticles, designed for antibacterial biomedical coatings. Antimicrobial activities of titanium, TiO2 NT and ZnO/TiO2 NT surfaces were evaluated against bacterial strain typical for orthopaedic infections: S. epidermidis. TiO2 NT alone killed the free bacterial cells significantly but promoted their adhesion to the surfaces. The presence of moderate amount of ZnO nanoparticles significantly reduced the S. epidermidis cells adhesion and viability of bacterial cells in contact with modified surfaces. However, higher amount of loaded nanoZnO showed the reduced antimicrobial properties than the medium amount, suggesting the overdose effect.

【 授权许可】

Unknown