期刊论文详细信息
| Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society | |
| Neutrophils and inflammatory metabolism in antimicrobial functions of the mucosa | |
| 关键词: inflammation; infection; colitis; epithelium; hypoxia; | |
| DOI : 10.1189/jlb.3MR1114-556R | |
| 学科分类：生理学 | |
| 来源: Federation of American Societies for Experimental Biology | |
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【 摘 要 】
Inthismini‐review,wewilldiscussrecentfindingsthatimplicateneutrophilinfiltrationandfunctioninestablishingametabolicenvironmenttofacilitateefficientpathogenclearance.Fordecades,neutrophilshavebeenregardedasshortlived,nonspecificgranulocytes,equippedwithtoxicantimicrobialfactorsandarespiratoryburstgeneratingROS.RecentfindingsdemonstratetheimportanceofHIFsignalinginleukocytesandsurroundingtissuesduringinflammation.Here,wewillreviewthepotentialmechanismsandoutcomesofHIFstabilizationwithintheintestinalmucosa...
【 授权许可】
CC BY
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| RO201901231588295ZK.pdf | 591KB |  download |
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