Reconstruction of bone defect with autograft fibula and retained part of tibia after marginal resection of periosteal osteosarcoma: a case report

World Journal of Surgical Oncology

Yingze Zhang¹  Chenguang Du¹  Jianheng Li²  Wei Chen¹  Tongyu Hu¹ 

[1] Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, People’s Republic of China;Department of Orthopedic Surgery, Chinese People’s Liberation Army No. 256 Hospital, Shijiazhuang 050041, Hebei, People’s Republic of China

关键词: Chemotherapy;    Retained tibia;    Autograft fibula;    Marginal resection;    Periosteal osteosarcoma;   

Others  :  1218713
DOI  :  10.1186/s12957-015-0618-2

 received in 2014-08-29, accepted in 2015-06-10,  发布年份 2015

【 摘 要 】

Periosteal osteosarcoma is a rare subtype of osteosarcoma. Wide surgical removal is the commonly used treatment-method algorithm. However, the limb-salvage procedure of periosteal osteosarcoma in the distal tibia is a technical challenge to orthopedic surgeons because of the scarcity of soft tissue and subcutaneous nature in the anteromedial aspect. We encountered a 16-year-old female patient with periosteal osteosarcoma in the distal half of the left tibia diagnosed preoperatively based upon the CT images and a needle biopsy. A unique identical surgical technique was applied in the case, including marginal resection of the periosteal osteosarcoma with part of the tibia retained at the same level of bone defect and reconstruction using the autologous fibula graft. A combination of cisplatin and doxorubicin was received as chemotherapy after the operation. Postoperative incisional biopsy was performed, and the hematoxylin-eosin-stained results confirmed the diagnosis of periosteal osteosarcoma. The patient was followed up for 11 years. Radiological and clinical evaluation was performed at each follow-up. The retained tibia incorporated well with the fibula autograft, and excellent limb functional recovery was achieved. The patient was free from neoplastic disease at the latest follow-up. In conclusion, young patients with periosteal osteosarcoma without intramedullary involvement can be treated by marginal resection of the lesion with part of the tibia retained at the level of bone defect and reconstructed using a long autologous fibula graft. Subsequent chemotherapy with administration of cisplatin and doxorubicin is recommended.

【 授权许可】

   
2015 Hu et al.

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