Congenital nasolacrimal duct fistula in Brown Swiss cattle

BMC Veterinary Research

Cord Drögemüller¹  Simon Jacober²  Ueli Braun² 

[1] Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland;Department of Farm Animals, Vetsuisse-Faculty, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland

关键词: Congenital anomaly;    Nasolacrimal duct fistula;    Nasolacrimal duct;    Cattle;   

Others  :  1119326
DOI  :  10.1186/1746-6148-10-44

 received in 2013-08-26, accepted in 2014-02-15,  发布年份 2014

【 摘 要 】

Background

An increased incidence of nasolacrimal duct fistula in the offspring of dam J and three of her sons (bulls A, B and C) prompted a study to investigate the prevalence and clinical manifestation of this anomaly. The dam J, bull B, 255 direct offspring of bulls A, B, and C and eight other direct and indirect offspring of cow J were examined. The periocular region of each animal was examined for unilateral or bilateral nasolacrimal duct fistula and the location, appearance and size of the lesions.

Results

Of 265 cattle examined, 54 had unilateral (n = 24) or bilateral fistula (n = 30). The prevalence of affected offspring differed significantly among the three bulls. The fistulae were located medial to the medial canthus of the eye and were 1 to 10 mm (median, 1 mm) in height and 1 to 12 mm (median, 2 mm) in length. The shape of the opening was circular in 58, oval in 23 and slit-like in three. One other animal had a large opening with an atypical shape and another had an abnormal medial canthus with several fistulous openings. Seventy openings were pigmented and 52 were hairless. The fistulae were clinically significant in 12 animals.

Conclusions

The findings suggest a hereditary cause of nasolacrimal duct fistula in Brown Swiss cattle.

【 授权许可】

   
2014 Braun et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

Figure 3.

Figure 4.

【 参考文献 】

• [1]Yuen SJA, Oley C, Sullivan TJ: Lacrimal outflow dysgenesis. Ophthalmology 2004, 11:1782-1790.
• [2]Simoens P: Der Tränenapparat. In Anatomie für die Tiermedizin. Edited by Salomon FV, Geyer H, Gille U. Stuttgart: Enke Verlag; 2008:603-605.
• [3]Zhuang L, Sylvester CL, Simons JP: Bilateral congenital lacrimal fistulae: a case report and review of the literature. Laryngoscope 2010, 120(Suppl. 4):S230.
• [4]Latimer CA, Wyman M: Atresia of the nasolacrimal duct in three horses. J Am Vet Med Assoc 1984, 184:989-992.
• [5]Wilkie DA, Rings DM: Repair of anomalous nasolacrimal duct in a bull by use of conjunctivorhinostomy. J Am Vet Med Assoc 1990, 196:1647-1650.
• [6]Grahn BH, Wolfer J, Cullen CL: What is your diagnosis and therapeutic plan? Congenital atresia of the left nasolacrimal duct. Can Vet J 1999, 40:71-72.
• [7]Heider L, Wyman M, Burt J, Root C, Gardner H: Nasolacrimal duct anomaly in calves. J Am Vet Med Assoc 1975, 167:145-147.
• [8]McLaughlin SA, Brightman AH, Nelson DR: Nasolacrimal duct anomaly in a Holstein calf. Agri-Pract 1985, 6(No 7):30-31.
• [9]Braun U, Spiess B, Matheis F, Schnetzler C, Trösch L, Drögemüller C, Gerspach C: Bilateral congenital lacrimal fistula in a Brown Swiss bull. Schweiz Arch Tierheilk 2012, 154:121-123.
• [10]Jacober S: Untersuchungen bei Rindern mit kongenitalen Tränenfisteln. Master Thesis: University of Zurich; 2013.
• [11]Jones LT, Wobig JL: The lacrimal “Anlage Duct”. In Surgery of the Eyelids and Lacrimal System. Birmingham: Aesculapius Publishing Company; 1978:167-173.
• [12]Maden A, Yilmaz S, Ture M: Hereditary lacrimal fistula. Orbit 2008, 27:69-72.
• [13]Worede GM, Forabosco F, Zumbach B, Palucci V, Jorjani H: Evaluation of genetic variation in the international Brown Swiss population. Animal 2013, 7:1060-1066.