Poor sleep quality is associated with increased arterial stiffness in Japanese patients with type 2 diabetes mellitus

BMC Endocrine Disorders

Hirotaka Watada³  Yoshio Fujitani⁴  Masahiko Gosho²  Akio Kanazawa⁶  Hidenori Ishida¹  Yuki Someya⁴  Shiho Nakayama⁴  Atsuko Tamasawa¹  Miyoko Saito¹  Takeshi Osonoi¹  Tomoya Mita⁵  Yusuke Osonoi⁴ 

[1] Naka Memorial Clinic, 745-5, Nakadai, Naka City 311-0113, Ibaraki, Japan;Department of Clinical Trial and Clinical Epidemiology, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba 305-8575, Ibaraki, Japan;Sportology Center, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyoku 113-8421, Tokyo, Japan;Department of Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyoku 113-8421, Tokyo, Japan;Center for Molecular Diabetology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyoku 113-8421, Tokyo, Japan;Center for Therapeutic Innovations in Diabetes, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyoku 113-8421, Tokyo, Japan

关键词: Japanese;    Type 2 diabetes mellitus;    Arterial stiffness;    Sleep quality;   

Others  :  1215937
DOI  :  10.1186/s12902-015-0026-1

 received in 2015-02-05, accepted in 2015-06-01,  发布年份 2015

【 摘 要 】

Background

While poor sleep quality can worsen cardiovascular risk factors such as glucose and lipid profiles in patients with type 2 diabetes mellitus (T2DM), the relationship between sleep quality and atherosclerosis remains largely unknown. The aim of this study was to examine this relationship.

Methods

The study participants comprised 724 Japanese T2DM outpatients free of history of cardiovascular diseases. The relationships between sleep quality (assessed by the Pittsburgh Sleep Quality Index (PSQI)) and various clinical and laboratory parameters were investigated.

Results

The mean PSQI was 5.1 ± 3.0 (±SD). Patients were divided into three groups based on the total PSQI score; subjects with good sleep quality (n = 462), average sleep quality (n = 185), and poor sleep quality (n = 77). In the age/gender-adjusted model, patients with poor sleep quality tended to be obese, evening type and depressed. However, other lifestyles showed no significant trends. Alanine aminotransferase, fasting blood glucose, HbA1c, systolic blood pressure, urinary albumin excretion, and brachial-ankle pulse wave velocity (baPWV) tended to be higher in patients with poor sleep quality. High baPWV was the only parameter that correlated with poor sleep in a model adjusted for several other lifestyle factors.

Conclusions

Our study indicates that poor sleep quality in T2DM patients correlates with increased arterial wall stiffness, a marker of atherosclerosis and a risk factor for cardiovascular diseases.

【 授权许可】

   
2015 Osonoi et al.

【 参考文献 】

• [1]Stevens RJ, Kothari V, Adler AI, Stratton IM. The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56). Clin Sci. 2001; 101(6):671-9.
• [2]Balkau B, Hu G, Qiao Q, Tuomilehto J, Borch-Johnsen K, Pyorala K, Group DS. Prediction of the risk of cardiovascular mortality using a score that includes glucose as a risk factor. The DECODE Study. Diabetologia. 2004; 47(12):2118-28.
• [3]Ayas NT, White DP, Al-Delaimy WK, Manson JE, Stampfer MJ, Speizer FE, Patel S, Hu FB. A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care. 2003; 26(2):380-4.
• [4]Kawakami N, Takatsuka N, Shimizu H. Sleep disturbance and onset of type 2 diabetes. Diabetes Care. 2004; 27(1):282-3.
• [5]Nilsson PM, Roost M, Engstrom G, Hedblad B, Berglund G. Incidence of diabetes in middle-aged men is related to sleep disturbances. Diabetes Care. 2004; 27(10):2464-9.
• [6]Mallon L, Broman JE, Hetta J. High incidence of diabetes in men with sleep complaints or short sleep duration: a 12-year follow-up study of a middle-aged population. Diabetes Care. 2005; 28(11):2762-7.
• [7]Bjorkelund C, Bondyr-Carlsson D, Lapidus L, Lissner L, Mansson J, Skoog I, Bengtsson C. Sleep disturbances in midlife unrelated to 32-year diabetes incidence: the prospective population study of women in Gothenburg. Diabetes Care. 2005; 28(11):2739-44.
• [8]Meisinger C, Heier M, Loewel H. Sleep disturbance as a predictor of type 2 diabetes mellitus in men and women from the general population. Diabetologia. 2005; 48(2):235-41.
• [9]Yaggi HK, Araujo AB, McKinlay JB. Sleep duration as a risk factor for the development of type 2 diabetes. Diabetes Care. 2006; 29(3):657-61.
• [10]Ayas NT, White DP, Manson JE, Stampfer MJ, Speizer FE, Malhotra A, Hu FB. A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med. 2003; 163(2):205-9.
• [11]Trento M, Broglio F, Riganti F, Basile M, Borgo E, Kucich C, Passera P, Tibaldi P, Tomelini M, Cavallo F et al.. Sleep abnormalities in type 2 diabetes may be associated with glycemic control. Acta Diabetol. 2008; 45(4):225-9.
• [12]Ohkuma T, Fujii H, Iwase M, Kikuchi Y, Ogata S, Idewaki Y, Ide H, Doi Y, Hirakawa Y, Nakamura U et al.. Impact of sleep duration on obesity and the glycemic level in patients with type 2 diabetes: the Fukuoka Diabetes Registry. Diabetes Care. 2013; 36(3):611-7.
• [13]Knutson KL, Ryden AM, Mander BA, Van Cauter E. Role of sleep duration and quality in the risk and severity of type 2 diabetes mellitus. Arch Intern Med. 2006; 166(16):1768-74.
• [14]Tsai YW, Kann NH, Tung TH, Chao YJ, Lin CJ, Chang KC, Chang SS, Chen JY. Impact of subjective sleep quality on glycemic control in type 2 diabetes mellitus. Fam Pract. 2012; 29(1):30-5.
• [15]Williams CJ, Hu FB, Patel SR, Mantzoros CS. Sleep duration and snoring in relation to biomarkers of cardiovascular disease risk among women with type 2 diabetes. Diabetes Care. 2007; 30(5):1233-40.
• [16]Wan Mahmood WA, Draman Yusoff MS, Behan LA, Di Perna A, Kyaw Tun T, McDermott J, Sreenan S. Association between Sleep Disruption and Levels of Lipids in Caucasians with Type 2 Diabetes. Int J Endocrinol. 2013; 2013:341506.
• [17]Ohkuma T, Fujii H, Iwase M, Ogata-Kaizu S, Ide H, Kikuchi Y, Idewaki Y, Jodai T, Hirakawa Y, Nakamura U et al.. Association between sleep duration and urinary albumin excretion in patients with type 2 diabetes: the Fukuoka diabetes registry. PLoS One. 2013; 8(11): Article ID e78968
• [18]Tomiyama H, Koji Y, Yambe M, Shiina K, Motobe K, Yamada J, Shido N, Tanaka N, Chikamori T, Yamashina A. Brachial – ankle pulse wave velocity is a simple and independent predictor of prognosis in patients with acute coronary syndrome. Circ J. 2005; 69(7):815-22.
• [19]Miyano I, Nishinaga M, Takata J, Shimizu Y, Okumiya K, Matsubayashi K, Ozawa T, Sugiura T, Yasuda N, Doi Y. Association between brachial-ankle pulse wave velocity and 3-year mortality in community-dwelling older adults. Hypertens Res. 2010;33(7):678–82.
• [20]Nakamura M, Yamashita T, Yajima J, Oikawa Y, Sagara K, Koike A, Kirigaya H, Nagashima K, Sawada H, Aizawa T et al.. Brachial-ankle pulse wave velocity as a risk stratification index for the short-term prognosis of type 2 diabetic patients with coronary artery disease. Hypertens Res. 2010; 33(10):1018-24.
• [21]Maeda Y, Inoguchi T, Etoh E, Kodama Y, Sasaki S, Sonoda N, Nawata H, Shimabukuro M, Takayanagi R. Brachial-ankle pulse wave velocity predicts all-cause mortality and cardiovascular events in patients with diabetes: the Kyushu prevention study for atherosclerosis. Diabetes care 2014;25(3):359–64.
• [22]Osonoi Y, Mita T, Osonoi T, Saito M, Tamasawa A, Nakayama S, Someya Y, Ishida H, Kanazawa A, Gosho A, et al. Morningness Eveningness Questionnaire score and metabolic parameters in patients with type 2 diabetes mellitus. Chronobiol Int. Chronobiol Int. 2014 31(9):1017–23.
• [23]Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989; 28(2):193-213.
• [24]Hone JA, Ostberg O. A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. Int J Chronobiol. 1976; 4:97-110.
• [25]Beck AT, Steer RA, Brown GK. Manual for the Beck Depression Inventory-II. Psychological Corporation, San Antonio, TX; 1996.
• [26]Standard tables of food composition in Japan (in Japanese). 5th ed. Printing Bureau of the Ministry of Finance, Tokyo; 2005.
• [27]Craig CL, Marshall AL, Sjostrom M, Bauman AE, Booth ML, Ainsworth BE, Pratt M, Ekelund U, Yngve A, Sallis JF et al.. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003; 35(8):1381-95.
• [28]Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, Yamagata K, Tomino Y, Yokoyama H, Hishida A. Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis. 2009; 53(6):982-92.
• [29]Takeno K, Mita T, Nakayama S, Goto H, Komiya K, Abe H, Ikeda F, Shimizu T, Kanazawa A, Hirose T et al.. Masked hypertension, endothelial dysfunction, and arterial stiffness in type 2 diabetes mellitus: a pilot study. Am J Hypertens. 2012; 25(2):165-70.
• [30]Yamashina A, Tomiyama H, Takeda K, Tsuda H, Arai T, Hirose K, Koji Y, Hori S, Yamamoto Y. Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement. Hypertens Res. 2002; 25(3):359-64.
• [31]Haack M, Sanchez E, Mullington JM. Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. Sleep. 2007; 30(9):1145-52.
• [32]Zhang J, Ma RC, Kong AP, So WY, Li AM, Lam SP, Li SX, Yu MW, Ho CS, Chan MH et al.. Relationship of sleep quantity and quality with 24-hour urinary catecholamines and salivary awakening cortisol in healthy middle-aged adults. Sleep. 2011; 34(2):225-33.
• [33]Swierblewska E, Hering D, Kara T, Kunicka K, Kruszewski P, Bieniaszewski L, Boutouyrie P, Somers VK, Narkiewicz K. An independent relationship between muscle sympathetic nerve activity and pulse wave velocity in normal humans. J Hypertens. 2010; 28(5):979-84.
• [34]Iwasaki M, Hirose T, Mita T, Sato F, Ito C, Yamamoto R, Someya Y, Yoshihara T, Tamura Y, Kanazawa A et al.. Morningness-eveningness questionnaire score correlates with glycated hemoglobin in middle-aged male workers with type 2 diabetes mellitusMorningness. J Diabetes Investig. 2013; 4(4):376-81.
• [35]Reutrakul S, Hood MM, Crowley SJ, Morgan MK, Teodori M, Knutson KL, Van Cauter E. Chronotype is independently associated with glycemic control in type 2 diabetes. Diabetes Care. 2013; 36(9):2523-9.
• [36]Musselman DL, Betan E, Larsen H, Phillips LS. Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment. Biol Psychiatry. 2003; 54(3):317-29.