Mathematical model of the chromatin structure of the nuclei of blood cells

5th International Conference on "Problems of Mathematical and Theoretical Physics and Mathematical Modelling"

物理学;数学

Nikitaev, V.G.^1 ; Nagornov, O.V.^1 ; Pronichev, A.N.^1 ; Dmitrieva, V.V.^1 ; Polyakov, E.V.^1

National Research Nuclear University, MEPhI (Moscow Engineering Physics Institute), 31 Kashirskoe shosse, Moscow

115409, Russia^1

关键词: Acute leukemia;    Blood cells;    Chromatin structure;    Formation of image;    Texture features;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/788/1/012056/pdf
DOI  :  10.1088/1742-6596/788/1/012056

来源: IOP

【 摘 要 】

This paper describes the model of images of the nuclei of blood cells for research informative texture features in the diagnostics of acute leukemias on the basis of computer microscopy. The proposed model allows to simulate the structure of chromatin and factors distorting the signal in the formation of image.