The influence of physical factors on recognizing blood cells in the computer microscopy systems of acute leukemia diagnosis

1st International Symposium 'Physics, Engineering and Technologies for Bio-Medicine'

医药卫生;物理学;工业技术

Nikitaev, V.G.^1 ; Pronichev, A.N.^1 ; Polyakov, E.V.^1 ; Dmitrieva, V.V.^1 ; Tupitsyn, N.N.^2 ; Frenkel, M.A.^2 ; Mozhenkova, A.V.^2

National Research Nuclear University, MEPhI (Moscow Engineering Physics Institute), Kashirskoe shosse 31, Moscow

115409, Russia^1

N.N. Blokhin Russian Cancer Research Center, Kashirskoe shosse 23, Moscow

115478, Russia^2

关键词: Acute leukemia;    Blood cells;    Bone marrow;    Color space;    Microscopy systems;    Physical factors;    Texture characteristics;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/784/1/012042/pdf
DOI  :  10.1088/1742-6596/784/1/012042

来源: IOP

【 摘 要 】

The work investigated the effect of the choice of color space component on blood cell detection based on the calculation of texture attributes of blood cells nuclei in bone marrow. The study identified the most informative color space and texture characteristics of blood cells, designed for components of these spaces. Significance ratio was introduced to assess the quality of features. We offered features that have enabled to divide lymphocytes from lymphoblasts. The selection of the features was based on the results of the data analysis.