HOS cell adhesion on Ti6Al4V surfaces texturized by laser engraving

3rd International Meeting for Researchers in Materials and Plasma Technology; 1st Symposium on Nanoscience and Nanotechnology

物理学;材料科学

Sandoval Amador, A.^1 ; Carreño Garcia, H.^1 ; Escobar Rivero, P.^1 ; Peña Ballesteros, D.Y.^1 ; Estupiñán Duran, H.A.^2

Universidad Industrial de Santander (UIS), Bucaramanga, Colombia^1

Universidad Nacional de Colombia, Medellín, Colombia^2

关键词: Cell spreading;    Chemical compositions;    Fetal bovine serum;    Human osteosarcoma;    Incubation time;    Laser engraving;    Sample surface;    Test surfaces;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/687/1/012012/pdf
DOI  :  10.1088/1742-6596/687/1/012012

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

The cell adhesion of the implant is determinate by the chemical composition, topography, wettability, surface energy and biocompatibility of the biomaterial. In this work the interaction between human osteosarcoma HOS cells and textured Ti6Al4V surfaces were evaluated. Ti6Al4V surfaces were textured using a CO2laser in order to obtain circular spots on the surfaces. Test surfaces were uncoated (C1) used as a control surface, and surfaces with points obtained by laser engraving, with 1mm spacing (C2) and 0.5mm (C3). The HOS cells were cultured in RPMI-1640 medium with 10% fetal bovine serum and 1% antibiotics. No cells toxicity after one month incubation time occurred. The increased cell adhesion and cell spreading was observed after 1, 3 and 5 days without significant differences between the sample surfaces (C2 and C3) and control (uncoated) at the end of the experiment.