An evaluation of the clinical potential of tissue diffraction studies

International Conference on Bio-Medical Instrumentation and related Engineering and Physical Sciences

物理学;医药卫生

Speller, R.^1 ; Abuchi, S.^1 ; Zheng, Y.^1 ; Vassiljev, N.^1 ; Konstantinidis, A.^2 ; Griffiths, J.^1,3

Department of Medical Physics and Biomedical Engineering, UCL, London

WC1E 6BT, United Kingdom^1

Diagnostic Radiology and Radiation Protection, Christie Medical Physics and Engineering, Christie NHS Foundation Trust, Manchester

M20 4BX, United Kingdom^2

Institute of Biomedical Engineering, UCL, London

WC1E 6BT, United Kingdom^3

关键词: Breast Cancer;    Breast tissues;    Diffraction profiles;    Diffraction studies;    Molecular signatures;    Patient management;    Tissue types;    Xray imaging;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/637/1/012026/pdf
DOI  :  10.1088/1742-6596/637/1/012026

学科分类：卫生学

来源: IOP

【 摘 要 】

Medical imaging is a long established part of patient management in the treatment of disease. However, in most cases it only provides anatomical detail and does not provide any form of tissue characterisation. This is particularly true for X-ray imaging. Recent studies on tissue diffraction have shown that true molecular signatures can be derived for different tissue types. Breast cancer samples and liver tissue have been studied. It has been shown that diffraction profiles can be traced away from the primary tumour in excised breast tissue samples and that potentially 3mm fat nodules in liver tissue can be identified in patients at acceptable doses.